Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

Key facts

Copied from the official Grants.gov record. Last verified October 29, 2026.

Program name

Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

Issuing agency

National Institutes of Health (Department of Health and Human Services)

Opportunity number

PAR-27-039

Funding type

Grant

Funding purpose

Health

Status

Forecasted

Application deadline

Forecasted · estimated close January 5, 2027 (agency estimate)

Agency estimates

Estimated posting: November 5, 2026. Estimated award date: June 1, 2027. Estimates can change.

Published award range

Not published by the agency

Cost sharing or match required

No

Eligible applicants (official categories)

• Small businesses

Relevant to

BusinessesHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations.

Geographic restrictions

None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.

Assistance Listing (CFDA)

93.113, 93.121, 93.143, 93.172, 93.173, 93.213, 93.233, 93.273, 93.279, 93.350, 93.361, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.859, 93.865, 93.866, 93.867, 93.879

Official source

View on Grants.gov ↗

Application URL

www.grants.gov/search-results-detail/362576 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.

Source identifier

Grants.gov opportunity ID 362576 · Funding opportunity number PAR-27-039

Posted

May 27, 2026 · Source last updated May 27, 2026

Last verified

October 29, 2026 (against Grants.gov)

Data completeness

92% of key fields published by the sourceNot published: published funding range.

Record confidence

mediumforecast — dates and amounts are agency estimates.

Eligibility details (from the agency)

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.

Description (from the official listing)

The National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC), including the participating Institutes, Centers and Offices, intend to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I, and Fast-Track (NIH only) grant applications for the Small Business Transition Grant. Through this NOFO, NIH and CDC will support early-career scientists as they transition into entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R43/R44 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH and CDC awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project.

Agency contact

NIH SEED (Small business Education and Entrepreneurial Development) Office of Extramural Research (OER)
SEEDinfo@nih.gov