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Forecasted · Grant

Forecast to Renew the Notice of Funding Opportunity Announcement for the Multiple Chronic Disease Research Centers

National Institutes of Health, Department of Health and Human Services

Key facts

Copied from the official Grants.gov record. Last verified October 29, 2026.

Program name
Forecast to Renew the Notice of Funding Opportunity Announcement for the Multiple Chronic Disease Research Centers
Issuing agency
National Institutes of Health (Department of Health and Human Services)
Opportunity number
FOR-MD-25-002
Funding type
Grant
Funding purpose
Health
Status
Forecasted
Application deadline
Forecasted · estimated close July 25, 2025 (agency estimate)
Agency estimates
Estimated posting: May 16, 2025. Estimated award date: September 30, 2025. Estimates can change.
Published award range
Not published by the agency
Estimated total program funding
$55,000,000
Expected number of awards
11
Cost sharing or match required
No
Eligible applicants (official categories)
  • State governments
  • County governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Small businesses
Relevant to
Businesses and NonprofitsHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
Geographic restrictions
None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
Assistance Listing (CFDA)
93.307
Official source
View on Grants.gov ↗
Application URL
www.grants.gov/search-results-detail/358870 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
Source identifier
Grants.gov opportunity ID 358870 · Funding opportunity number FOR-MD-25-002
Posted
May 12, 2025 · Source last updated May 12, 2025
Last verified
October 29, 2026 (against Grants.gov)
Data completeness
83% of key fields published by the sourceNot published: published funding range, eligibility criteria text.
Record confidence
mediumforecast — dates and amounts are agency estimates.

Description (from the official listing)

This forecast is to renew the Notice of Funding Opportunity (NOFO) for the Multiple Chronic Disease Research Centers (RFA-MD-21-007). This initiative will support existing and new regional comprehensive research centers to optimize prevention, diagnosis, treatment and management of multiple chronic diseases (MCDs) and to improve health outcomes among pediatric and adult populations experiencing health disparities. The centers will focus on innovative research that: (1) develops, tests, and evaluates novel models or strategies, and/or (2) implements effective interventions in various settings such as community or healthcare settings/systems. Chronic diseases, such as cardiovascular diseases, cancer, diabetes, and chronic lower respiratory diseases, are among the leading causes of morbidity and mortality in the U.S. The prevalence of chronic health conditions among U.S. children and adolescents (especially cardiometabolic diseases) is also increasing. The effective integration and implementation of evidence-based interventions for both adults and children with comorbid chronic conditions remains understudied and is a priority. Each Center must address two or more chronic conditions that commonly co-occur and/or share common social context, etiological pathways, or risk factors and management strategies. Research projects that advance the Make America Healthy Again Commission goals, with a focus on addressing disparities in the prevention or effective diagnosis, treatment and management of chronic conditions will be prioritized. In addition, research design and methodologies…

Read the full description

This forecast is to renew the Notice of Funding Opportunity (NOFO) for the Multiple Chronic Disease Research Centers (RFA-MD-21-007). This initiative will support existing and new regional comprehensive research centers to optimize prevention, diagnosis, treatment and management of multiple chronic diseases (MCDs) and to improve health outcomes among pediatric and adult populations experiencing health disparities. The centers will focus on innovative research that: (1) develops, tests, and evaluates novel models or strategies, and/or (2) implements effective interventions in various settings such as community or healthcare settings/systems. Chronic diseases, such as cardiovascular diseases, cancer, diabetes, and chronic lower respiratory diseases, are among the leading causes of morbidity and mortality in the U.S. The prevalence of chronic health conditions among U.S. children and adolescents (especially cardiometabolic diseases) is also increasing. The effective integration and implementation of evidence-based interventions for both adults and children with comorbid chronic conditions remains understudied and is a priority. Each Center must address two or more chronic conditions that commonly co-occur and/or share common social context, etiological pathways, or risk factors and management strategies. Research projects that advance the Make America Healthy Again Commission goals, with a focus on addressing disparities in the prevention or effective diagnosis, treatment and management of chronic conditions will be prioritized. In addition, research design and methodologies that are replicable, reproducible and generalizable are priorities. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the P50 (Critical Trial Required) activity code. Investigators with expertise and insights into the proposed scientific areas are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in clinical, health services, behavioral interventions, implementation science, community engaged research, and clinical care will be encouraged, and these investigators should also consider applying for this NOFO.

Agency contact

Dolly Penn, MD, MSCR National Institute on Minority Health and Health Disparities (NIMHD)
Dolly.penn@nih.gov

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