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Forecasted · Cooperative Agreement

Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center

National Institutes of Health, Department of Health and Human Services

Key facts

Copied from the official Grants.gov record. Last verified October 29, 2026.

Program name
Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center
Issuing agency
National Institutes of Health (Department of Health and Human Services)
Opportunity number
PAR-27-136
Funding type
Cooperative Agreement
Funding purpose
Health
Status
Forecasted
Application deadline
Forecasted · estimated close May 25, 2027 (agency estimate)
Agency estimates
Estimated posting: March 25, 2027. Estimated award date: April 25, 2028. Estimates can change.
Published award range
Not published by the agency
Cost sharing or match required
No
Eligible applicants (official categories)
  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Small businesses
  • Others (see Additional Information on Eligibility)
Relevant to
Businesses and NonprofitsHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
Geographic restrictions
None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
Assistance Listing (CFDA)
93.853
Official source
View on Grants.gov ↗
Application URL
www.grants.gov/search-results-detail/363837 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
Source identifier
Grants.gov opportunity ID 363837 · Funding opportunity number PAR-27-136
Posted
September 10, 2026 · Source last updated September 10, 2026
Last verified
October 29, 2026 (against Grants.gov)
Data completeness
92% of key fields published by the sourceNot published: published funding range.
Record confidence
mediumforecast — dates and amounts are agency estimates.

Eligibility details (from the agency)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

Description (from the official listing)

NINDS intends to support a Diagnostic Research Innovation Center (DRIC) for the next phase of the Undiagnosed Diseases Network (UDN). The new Network is expected to include a Clinical and Data Coordinating Center (CDCC), geographically distributed clinical Networks of Diagnostic Excellence (NODEs), the NIH Undiagnosed Diseases Program (UDP), a DRIC, the UDN Foundation, patient advocacy organizations, NIH, and other stakeholders. The DRIC will contribute to the diagnosis of UDN participants, including participating in the systematic re-evaluation of unsolved UDN cases from previous phases of the UDN.The DRIC is expected to test and advance innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions. Working closely with clinical NODEs, the UDP, the CDCC, and other UDN stakeholders, the DRIC will support the generation and testing of diagnostic hypotheses including providing expertise and resources in advanced sequencing and multi-omics, gene function studies in animal and human in vitro models, and the development of non-genetic diagnostic strategies. Collaborating with the Network, the DRIC will contribute to the discovery of novel disease-associated genes and genomic variants, non-genetic contributors to UDN phenotypes, and the identification of new diseases and syndromes. Support is expected for an integrated center that brings together complementary capabilities and investigators with demonstrated scientific synergy and prior collaboration. Applications are not being solicited at this time. This Forecast is being published to provide…

Read the full description

NINDS intends to support a Diagnostic Research Innovation Center (DRIC) for the next phase of the Undiagnosed Diseases Network (UDN). The new Network is expected to include a Clinical and Data Coordinating Center (CDCC), geographically distributed clinical Networks of Diagnostic Excellence (NODEs), the NIH Undiagnosed Diseases Program (UDP), a DRIC, the UDN Foundation, patient advocacy organizations, NIH, and other stakeholders. The DRIC will contribute to the diagnosis of UDN participants, including participating in the systematic re-evaluation of unsolved UDN cases from previous phases of the UDN.The DRIC is expected to test and advance innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions. Working closely with clinical NODEs, the UDP, the CDCC, and other UDN stakeholders, the DRIC will support the generation and testing of diagnostic hypotheses including providing expertise and resources in advanced sequencing and multi-omics, gene function studies in animal and human in vitro models, and the development of non-genetic diagnostic strategies. Collaborating with the Network, the DRIC will contribute to the discovery of novel disease-associated genes and genomic variants, non-genetic contributors to UDN phenotypes, and the identification of new diseases and syndromes. Support is expected for an integrated center that brings together complementary capabilities and investigators with demonstrated scientific synergy and prior collaboration. Applications are not being solicited at this time. This Forecast is being published to provide potential applicants time to plan, establish collaborations, and develop responsive projects.

Agency contact

UDN Program Staff
UDNProgramStaff@ninds.nih.gov

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