Forecasted · Cooperative Agreement
Notice of Intent to Publish a Funding Opportunity Announcement for ClinGen Genomic Curation Expert Panels
National Institutes of Health, Department of Health and Human Services
Key facts
Copied from the official Grants.gov record. Last verified October 29, 2026.
- Program name
- Notice of Intent to Publish a Funding Opportunity Announcement for ClinGen Genomic Curation Expert Panels
- Issuing agency
- National Institutes of Health (Department of Health and Human Services)
- Opportunity number
- NOT-HD-25-006
- Funding type
- Cooperative Agreement
- Funding purpose
- Health
- Status
- Forecasted
- Application deadline
- Forecasted · estimated close May 25, 2026 (agency estimate)
- Agency estimates
- Estimated posting: March 25, 2026. Estimated award date: April 1, 2027. Estimates can change.
- Published award range
- Not published by the agency
- Estimated total program funding
- $880,000
- Expected number of awards
- 4
- Cost sharing or match required
- No
- Eligible applicants (official categories)
- State governments
- County governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Relevant to
- Businesses and NonprofitsHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
- Geographic restrictions
- None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
- Assistance Listing (CFDA)
- 93.865
- Official source
- View on Grants.gov ↗
- Application URL
- www.grants.gov/search-results-detail/359827 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
- Source identifier
- Grants.gov opportunity ID 359827 · Funding opportunity number NOT-HD-25-006
- Posted
- June 25, 2025 · Source last updated June 25, 2025
- Last verified
- October 29, 2026 (against Grants.gov)
- Data completeness
- 83% of key fields published by the sourceNot published: published funding range, eligibility criteria text.
- Record confidence
- mediumforecast — dates and amounts are agency estimates.
Description (from the official listing)
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), with other NIH Institutes and Centers (ICs) - National Eye Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute on Deafness and Other Communication Disorders, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Center for Advancing Translational Sciences, and National Cancer Institute - intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the establishment and continuation of Genomic Curation Expert Panels that manually curate, review and define the clinical relevance of genes and variants as part of the NIH established and funded Clinical Genome Resource (ClinGen). Despite advances in genomic sequencing technology and increasing adoption in clinical practice, there are many genomic variants with unknown significance (VUS), and there is limited understanding of their function. This presents barriers to genomic and precision medicine. To address this need for better knowledge about the links between genes, variants, and disease, this NOFO will facilitate the development of Expert Panels to select genes and variants associated with diseases or conditions of high priority for participating NIH Institutes and Centers (ICs) and to systematically determine their clinical significance for diagnosis and treatment of these diseases or conditions. The Expert Panels funded through this NOFO are required to utilize the NHGRI ClinGen and the NCBI ClinVar…
Read the full description
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), with other NIH Institutes and Centers (ICs) - National Eye Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute on Deafness and Other Communication Disorders, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Center for Advancing Translational Sciences, and National Cancer Institute - intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the establishment and continuation of Genomic Curation Expert Panels that manually curate, review and define the clinical relevance of genes and variants as part of the NIH established and funded Clinical Genome Resource (ClinGen). Despite advances in genomic sequencing technology and increasing adoption in clinical practice, there are many genomic variants with unknown significance (VUS), and there is limited understanding of their function. This presents barriers to genomic and precision medicine. To address this need for better knowledge about the links between genes, variants, and disease, this NOFO will facilitate the development of Expert Panels to select genes and variants associated with diseases or conditions of high priority for participating NIH Institutes and Centers (ICs) and to systematically determine their clinical significance for diagnosis and treatment of these diseases or conditions. The Expert Panels funded through this NOFO are required to utilize the NHGRI ClinGen and the NCBI ClinVar procedures, interfaces, tools, and informatics infrastructure. Ultimately, these expert panels contribute to an authoritative, centralized, and public resource, through aggregation, evaluation, and sharing of expert-curated data about genetic conditions, and the variants that cause them.
Agency contact
Julia Jiaqi O’Reilly, PhD Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Jiaqi.OReilly@nih.gov