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Forecasted · Cooperative Agreement

NIOSH Centers of Excellence for Total Worker Health® (U19)

Centers for Disease Control and Prevention - ERA, Department of Health and Human Services

Key facts

Copied from the official Grants.gov record. Last verified October 29, 2026.

Program name
NIOSH Centers of Excellence for Total Worker Health® (U19)
Issuing agency
Centers for Disease Control and Prevention - ERA (Department of Health and Human Services)
Opportunity number
RFA-OH-27-049
Funding type
Cooperative Agreement
Funding purpose
Health
Status
Forecasted
Application deadline
Forecasted · estimated close February 26, 2027 (agency estimate)Agency note: October 05, 2027. All applications must be submitted no later than 11:59 pm local time of the applicant's organization.
Agency estimates
Estimated posting: November 16, 2026. Estimated award date: August 2, 2027. Estimates can change.
Published award range
$500,000 – $1,400,000
Estimated total program funding
$58,500,000
Expected number of awards
10
Cost sharing or match required
No
Eligible applicants (official categories)
  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Small businesses
  • Unrestricted (open to any type of entity, subject to any clarification in Additional Information on Eligibility)
Relevant to
Businesses and NonprofitsHow we determined this: Grants.gov lists eligibility as Unrestricted. Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
Geographic restrictions
None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
Assistance Listing (CFDA)
93.262
Official source
View on Grants.gov ↗
Application URL
www.grants.gov/search-results-detail/363369 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
Source identifier
Grants.gov opportunity ID 363369 · Funding opportunity number RFA-OH-27-049
Posted
July 28, 2026 · Source last updated July 28, 2026
Last verified
October 29, 2026 (against Grants.gov)
Data completeness
100% of key fields published by the source
Record confidence
mediumforecast — dates and amounts are agency estimates.

Eligibility details (from the agency)

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.

Description (from the official listing)

PURPOSENIOSH intends to support the Centers of Excellence in Total Worker Health® (TWH). These Centers will conduct rigorous research and translation activities to prevent harmful exposures, improve working conditions, and advance worker well-being. The Centers will develop practical, scalable solutions for employers and workers. All projects must use the NIOSH Worker Well-Being Questionnaire (WellBQ) and share data with the HERO Worker Well-Being Clearinghouse. Large Research Projects require economic evaluation. PRIORITY AREAS• High-risk occupations: First responders, vehicle mechanics, and technicians, with emphasis on occupational exposures, related health risks, and prevention strategies• Young workers, SMEs • Chronic disease• Mental health, stress• Substance use disorder• Artificial intelligence (AI), digital technologiesThis is a multi-component NOFO.COMPONENT STRUCTUREPercentages indicate maximum share of total budget.Overall Component (Required)Provides Center leadership and integration. Applicants should show strong coordination, scientific direction, and alignment across projects.Administration, Evaluation, and Emerging Issues Core (Required; up to 15%)Supports management and Center-wide evaluation. Applicants should describe oversight, data governance, and quality assurance.Optional activities include emerging issues and shared research resources.Outreach, Dissemination, and Impact Core (Required; up to 15%)Supports communication, worker/employer engagement, training, translation, implementation, and dissemination strategies.Research Projects (Required; about…

Read the full description

PURPOSENIOSH intends to support the Centers of Excellence in Total Worker Health® (TWH). These Centers will conduct rigorous research and translation activities to prevent harmful exposures, improve working conditions, and advance worker well-being. The Centers will develop practical, scalable solutions for employers and workers. All projects must use the NIOSH Worker Well-Being Questionnaire (WellBQ) and share data with the HERO Worker Well-Being Clearinghouse. Large Research Projects require economic evaluation. PRIORITY AREAS• High-risk occupations: First responders, vehicle mechanics, and technicians, with emphasis on occupational exposures, related health risks, and prevention strategies• Young workers, SMEs • Chronic disease• Mental health, stress• Substance use disorder• Artificial intelligence (AI), digital technologiesThis is a multi-component NOFO.COMPONENT STRUCTUREPercentages indicate maximum share of total budget.Overall Component (Required)Provides Center leadership and integration. Applicants should show strong coordination, scientific direction, and alignment across projects.Administration, Evaluation, and Emerging Issues Core (Required; up to 15%)Supports management and Center-wide evaluation. Applicants should describe oversight, data governance, and quality assurance.Optional activities include emerging issues and shared research resources.Outreach, Dissemination, and Impact Core (Required; up to 15%)Supports communication, worker/employer engagement, training, translation, implementation, and dissemination strategies.Research Projects (Required; about 60 to 70%)Includes all research activities. Applicants may propose a mix of projects. Research project distinctions are based on scope and complexity rather than cost. Projects should demonstrate scientific rigor and potential for sustained impact.Small Research Projects (Required; at least one project; up to 3 years)Exploratory, feasibility, early-stage intervention, surveillance, or measurement studies.Priority areas: high-risk occupations, young workers, SMEs.Should show innovation and potential to expand. Large Research Projects (Required; at least one project; up to 5 years)Multiyear etiologic, mechanistic, intervention, or translational studies.Priority areas: chronic disease, mental health, substance use disorder. Economic evaluation is required. Projects should include strong design and analytic plans. Pilot/Feasibility Program (Optional; 12–18 months) Short-term studies generating preliminary data or testing AI/digital technology approaches.

Agency contact

Maria Lioce, MD, Scientific Program Official
MLioce@cdc.gov

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