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Open (posted) · Grant

Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)

National Institutes of Health, Department of Health and Human Services

Key facts

Copied from the official Grants.gov record. Last verified October 30, 2026.

Program name
Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)
Issuing agency
National Institutes of Health (Department of Health and Human Services)
Opportunity number
PAR-25-282
Funding type
Grant
Funding purpose
Health
Status
Open (posted)
Application deadline
Closes January 7, 2028
Published award range
Not published by the agency
Cost sharing or match required
No
Eligible applicants (official categories)
  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Small businesses
  • Others (see Additional Information on Eligibility)
Relevant to
Businesses and NonprofitsHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
Geographic restrictions
None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
Assistance Listing (CFDA)
93.242, 93.313
Application URL
www.grants.gov/search-results-detail/357342 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
Source identifier
Grants.gov opportunity ID 357342 · Funding opportunity number PAR-25-282
Posted
November 22, 2024 · Source last updated November 22, 2024
Last verified
October 30, 2026 (against Grants.gov)
Data completeness
92% of key fields published by the sourceNot published: published funding range.
Record confidence
highVerified against the official source; key fields present; no open issues.

Eligibility details (from the agency)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Description (from the official listing)

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the emergence and worsening of mood and psychotic disorders (e.g., perimenopausal depression (PMD), generalized anxiety disorder, bipolar disorder and schizophrenia) during the menopause transition (MT) in an effort to identity targets for future development of novel treatment interventions. This funding opportunity aims to advance novel and innovative translational research to better comprehend the underlying neurobiological and behavioral mechanisms of mood and psychosis disorders and related symptoms during MT. This funding opportunity also encourages interdisciplinary researchers to collaborate on studies of mood and psychosis during the MT. Aspects of mood and psychosis disorders that are of interest include: classic depressive symptoms in combination with menopause symptoms (e.g., hot flashes, night sweats, sleep disturbance) and psychological challenges, the role of reproductive steroids in the regulation of mood and behavior during the MT, diagnosis of mood and psychosis symptoms at menopausal stage, investigation of co-occurring psychiatric and menopause symptoms, appreciation of psychosocial factors common in midlife, and differential diagnoses. Review criteria will focus on the comprehensiveness of the neurobiology and mechanisms of action underlying mood and psychosis symptoms and hypothesis-driven work.

Agency contact

NIH Grants Information grantsinfo@nih.gov
grantsinfo@nih.gov

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