Forecasted · Grant
Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)
National Institutes of Health, Department of Health and Human Services
Key facts
Copied from the official Grants.gov record. Last verified October 29, 2026.
- Program name
- Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)
- Issuing agency
- National Institutes of Health (Department of Health and Human Services)
- Opportunity number
- RFA-ES-27-009
- Funding type
- Grant
- Funding purpose
- Health
- Status
- Forecasted
- Application deadline
- Forecasted · estimated close January 5, 2027 (agency estimate)
- Agency estimates
- Estimated posting: December 4, 2026. Estimated award date: July 31, 2027. Estimates can change.
- Published award range
- $100,000 – $500,000
- Estimated total program funding
- $15,000,000
- Expected number of awards
- 20
- Cost sharing or match required
- No
- Eligible applicants (official categories)
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see Additional Information on Eligibility)
- Relevant to
- Businesses and NonprofitsHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
- Geographic restrictions
- None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
- Assistance Listing (CFDA)
- 93.113
- Official source
- View on Grants.gov ↗
- Application URL
- www.grants.gov/search-results-detail/363861 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
- Source identifier
- Grants.gov opportunity ID 363861 · Funding opportunity number RFA-ES-27-009
- Posted
- September 14, 2026 · Source last updated September 14, 2026
- Last verified
- October 29, 2026 (against Grants.gov)
- Data completeness
- 100% of key fields published by the source
- Record confidence
- mediumforecast — dates and amounts are agency estimates.
Eligibility details (from the agency)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;
Description (from the official listing)
The purpose of this funding opportunity is to support mechanistic research to understand how exposure to metals and metal-containing compounds alters biological processes relevant to human health. Of particular interest are studies that elucidate the absorption, distribution, transport, cellular trafficking, biological interactions, and mechanisms of action of metals, including mechanisms through which metals may alter immune homeostasis, cross the placental barrier, or gain access to and affect the central nervous system. Studies may employ experimental models, new approach methodologies, computational approaches, or leverage human biospecimens where these approaches are used to address defined mechanistic hypotheses.
Agency contact
NOFO.information@niehs.nih.gov
NOFO.information@niehs.nih.gov