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Forecasted · Grant

Mechanisms Underlying Olfactory Dysfunction in Aging and Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias

National Institutes of Health, Department of Health and Human Services

Key facts

Copied from the official Grants.gov record. Last verified October 29, 2026.

Program name
Mechanisms Underlying Olfactory Dysfunction in Aging and Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias
Issuing agency
National Institutes of Health (Department of Health and Human Services)
Opportunity number
RFA-AG-26-021
Funding type
Grant
Funding purpose
Health
Status
Forecasted
Application deadline
Forecasted · estimated close October 6, 2026 (agency estimate)
Agency estimates
Estimated posting: August 6, 2026. Estimated award date: July 6, 2027. Estimates can change.
Published award range
Not published by the agency
Cost sharing or match required
No
Eligible applicants (official categories)
  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Small businesses
  • Others (see Additional Information on Eligibility)
Relevant to
Businesses and NonprofitsHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
Geographic restrictions
None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
Assistance Listing (CFDA)
93.866
Official source
View on Grants.gov ↗
Application URL
www.grants.gov/search-results-detail/360893 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
Source identifier
Grants.gov opportunity ID 360893 · Funding opportunity number RFA-AG-26-021
Posted
November 20, 2025 · Source last updated November 20, 2025
Last verified
October 29, 2026 (against Grants.gov)
Data completeness
92% of key fields published by the sourceNot published: published funding range.
Record confidence
mediumforecast — dates and amounts are agency estimates.

Eligibility details (from the agency)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

Description (from the official listing)

The National Institute on Aging (NIA), with the National Institute on Deafness and Other Communication Disorders (NIDCD), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that investigate the mechanisms underlying the association between olfactory decline and aging or Alzheimer's disease (AD) and AD-related dementias (ADRD). Understanding these mechanisms may help inform the potential use of olfactory dysfunction with age as an indicator of various health outcomes in older adults (e.g. physical function) and as a predictor of AD/ADRD risk. Identifying circuit-level olfactory changes may also uncover novel targets for developing disease-modifying therapeutic strategies. Studies may include older adults and/or animal models and may employ a variety of approaches, including cellular, molecular, imaging, physiological, omics and new approach methodologies (NAMs) to address the research gaps.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the R01 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.

Agency contact

Coryse St. Hillaire-Clarke, Ph.D.
sthillaireclacn@mail.nih.gov

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