Forecasted · Cooperative Agreement
Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)
National Institutes of Health, Department of Health and Human Services
Key facts
Copied from the official Grants.gov record. Last verified October 29, 2026.
- Program name
- Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)
- Issuing agency
- National Institutes of Health (Department of Health and Human Services)
- Opportunity number
- RFA-ES-28-002
- Funding type
- Cooperative Agreement
- Funding purpose
- Health
- Status
- Forecasted
- Application deadline
- Forecasted · estimated close January 29, 2027 (agency estimate)
- Agency estimates
- Estimated posting: November 27, 2026. Estimated award date: December 1, 2027. Estimates can change.
- Published award range
- Up to $2,000,000
- Estimated total program funding
- $18,000,000
- Expected number of awards
- 6
- Cost sharing or match required
- No
- Eligible applicants (official categories)
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see Additional Information on Eligibility)
- Relevant to
- Businesses and NonprofitsHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
- Geographic restrictions
- None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
- Assistance Listing (CFDA)
- 93.113
- Official source
- View on Grants.gov ↗
- Application URL
- www.grants.gov/search-results-detail/362978 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
- Source identifier
- Grants.gov opportunity ID 362978 · Funding opportunity number RFA-ES-28-002
- Posted
- June 26, 2026 · Source last updated June 26, 2026
- Last verified
- October 29, 2026 (against Grants.gov)
- Data completeness
- 100% of key fields published by the source
- Record confidence
- mediumforecast — dates and amounts are agency estimates.
Eligibility details (from the agency)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations
Description (from the official listing)
The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose translational research hubs with multiple highly integrated components focused on research, capacity building, and community/public health translation for regionally relevant topics related to the health impacts of extreme weather and cumulative exposures, including but not limited to wildfire smoke, extreme heat, flooding, hurricanes, drought, and other climate-related hazards affecting populations at heightened risk across the lifespan. Responsive applications will be led by a multidisciplinary team of investigators with non-academic partners, such as state and local public health departments, community-based organizations, Tribal entities, health care systems, and emergency preparedness agencies. Consortia of multiple institutions are encouraged, particularly those that demonstrate meaningful community engagement and balanced, mutually beneficial partnership structures. Research can be situated at different nodes on the translational research continuum, spanning from fundamental to implementation research with a focus on being problem-based and solutions oriented, and should clearly inform pathways to support implementation, scalability, and measurable public health impact. Award recipients will be expected to collaborate with the HEW Research Coordination and Data Center(s) and other members of the HEW Community of Practice, including participation in data harmonization efforts, shared metrics development, and…
Read the full description
The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose translational research hubs with multiple highly integrated components focused on research, capacity building, and community/public health translation for regionally relevant topics related to the health impacts of extreme weather and cumulative exposures, including but not limited to wildfire smoke, extreme heat, flooding, hurricanes, drought, and other climate-related hazards affecting populations at heightened risk across the lifespan. Responsive applications will be led by a multidisciplinary team of investigators with non-academic partners, such as state and local public health departments, community-based organizations, Tribal entities, health care systems, and emergency preparedness agencies. Consortia of multiple institutions are encouraged, particularly those that demonstrate meaningful community engagement and balanced, mutually beneficial partnership structures. Research can be situated at different nodes on the translational research continuum, spanning from fundamental to implementation research with a focus on being problem-based and solutions oriented, and should clearly inform pathways to support implementation, scalability, and measurable public health impact. Award recipients will be expected to collaborate with the HEW Research Coordination and Data Center(s) and other members of the HEW Community of Practice, including participation in data harmonization efforts, shared metrics development, and cross-site dissemination activities. This NOFO will utilize the U54 activity code, that supports specialized centers that function as regional resources for targeted research initiatives, including support for infrastructure development, pilot projects, and partnerships with affected communities throughout the research lifecycle. The U54 is a cooperative agreement that anticipates substantial federal programmatic staff involvement to assist investigators in the achievement of project objectives, including coordination across funded hubs, strategic alignment with NIH priorities, and facilitation of cross-institute collaboration. Grant authorities that allow NIEHS to forecast this opportunity are as follows: 42 USC 285l (NIEHS specific); 42 USC sections 241 (NIH grant authorities).
Agency contact
NIEHS Division of Extramural Research and Training
NOFO.Information@niehs.nih.gov