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Forecasted · Cooperative Agreement, Grant

Continuation of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) (U24 Clinical Trial Not Allowed)

National Institutes of Health, Department of Health and Human Services

Key facts

Copied from the official Grants.gov record. Last verified October 29, 2026.

Program name
Continuation of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) (U24 Clinical Trial Not Allowed)
Issuing agency
National Institutes of Health (Department of Health and Human Services)
Opportunity number
RFA-AG-27-004
Funding type
Cooperative Agreement, Grant
Funding purpose
Health
Status
Forecasted
Application deadline
Forecasted · estimated close May 8, 2027 (agency estimate)
Agency estimates
Estimated posting: February 8, 2027. Estimated award date: April 30, 2028. Estimates can change.
Published award range
Not published by the agency
Cost sharing or match required
No
Eligible applicants (official categories)
  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Small businesses
  • Others (see Additional Information on Eligibility)
Relevant to
Businesses and NonprofitsHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
Geographic restrictions
None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
Assistance Listing (CFDA)
93.866
Official source
View on Grants.gov ↗
Application URL
www.grants.gov/search-results-detail/363945 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
Source identifier
Grants.gov opportunity ID 363945 · Funding opportunity number RFA-AG-27-004
Posted
September 24, 2026 · Source last updated September 24, 2026
Last verified
October 29, 2026 (against Grants.gov)
Data completeness
92% of key fields published by the sourceNot published: published funding range.
Record confidence
mediumforecast — dates and amounts are agency estimates.

Eligibility details (from the agency)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Description (from the official listing)

The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to support the continued operation and expansion of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) through a single U24 cooperative agreement award. The NOFO will be open to all eligible applicants.Established in 2022, the EL DMCC serves as the central hub for NIA’s human longevity translational research portfolio, integrating data and activities across studies to maximize the value of deeply phenotyped cohorts and associated genomic and multi-omics datasets.The DMCC currently plays a critical role in enabling cross-cohort analyses, coordinating collaborative research, and advancing shared data resources. Core functions include data harmonization and integration; development and implementation of common data standards; provision of statistical, computational, and artificial intelligence and machine learning (AI/ML) infrastructure and tools; coordination of cross-project collaborations; and managing shared data systems, including data storage, access, and platform operations.The DMCC also develops and maintains the ELITE (Exceptional Longevity Translational Resources) Portal, which provides secure access to harmonized datasets, analytical tools, and cloud-based computational workspaces. The DMCC supports controlled access to EL data and use of these resources by the research community and maintains ongoing efforts to ensure the Portal is interoperable with the NIA Alzheimer’s Disease Knowledge Portal and other data resources of the National Institutes…

Read the full description

The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to support the continued operation and expansion of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) through a single U24 cooperative agreement award. The NOFO will be open to all eligible applicants.Established in 2022, the EL DMCC serves as the central hub for NIA’s human longevity translational research portfolio, integrating data and activities across studies to maximize the value of deeply phenotyped cohorts and associated genomic and multi-omics datasets.The DMCC currently plays a critical role in enabling cross-cohort analyses, coordinating collaborative research, and advancing shared data resources. Core functions include data harmonization and integration; development and implementation of common data standards; provision of statistical, computational, and artificial intelligence and machine learning (AI/ML) infrastructure and tools; coordination of cross-project collaborations; and managing shared data systems, including data storage, access, and platform operations.The DMCC also develops and maintains the ELITE (Exceptional Longevity Translational Resources) Portal, which provides secure access to harmonized datasets, analytical tools, and cloud-based computational workspaces. The DMCC supports controlled access to EL data and use of these resources by the research community and maintains ongoing efforts to ensure the Portal is interoperable with the NIA Alzheimer’s Disease Knowledge Portal and other data resources of the National Institutes of Health, consistent with FAIR (Findable, Accessible, Interoperable, Reusable) data principles.Through the NOFO, the Coordinating Center will be expected to build on and expand these core functions by:Enhancing integration of increasingly large and diverse datasets across cohorts and speciesExpanding statistical, computational, and AI/ML capabilities and associated infrastructureDeveloping and refining methods and standards for multi-omics data harmonization and integrative analysesCoordinating and supporting collaborative research across NIA-funded projectsDeveloping and disseminating translational resources, including target nomination and prioritization resources, curated target knowledgebases, and inventories of candidate therapeutic targetsAdvancing the ELITE Portal, including improvements in data organization, search, visualization, interoperability, and cloud-based analytical environmentsStrengthening community engagement through training, workshops, and collaborative activitiesApplications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

Agency contact

NIA Scientific Contact
NIA-NOFO-Scientific@nih.gov

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