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Forecasted · Grant

Centers without Walls for mechanisms of neurodegeneration in Alzheimer’s disease-related dementias (ADRD)

National Institutes of Health, Department of Health and Human Services

Key facts

Copied from the official Grants.gov record. Last verified October 29, 2026.

Program name
Centers without Walls for mechanisms of neurodegeneration in Alzheimer’s disease-related dementias (ADRD)
Issuing agency
National Institutes of Health (Department of Health and Human Services)
Opportunity number
RFA-NS-26-032
Funding type
Grant
Funding purpose
Health
Status
Forecasted
Application deadline
Forecasted · estimated close October 1, 2026 (agency estimate)
Agency estimates
Estimated posting: May 18, 2026. Estimated award date: July 1, 2027. Estimates can change.
Published award range
Not published by the agency
Estimated total program funding
$10,000,000
Expected number of awards
5
Cost sharing or match required
No
Eligible applicants (official categories)
  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Small businesses
  • Others (see Additional Information on Eligibility)
Relevant to
Businesses and NonprofitsHow we determined this: Grants.gov eligibility includes small businesses or for-profit organizations. Grants.gov eligibility includes nonprofit organizations.
Geographic restrictions
None stated in structured data (federal opportunities are often nationwide). Check the eligibility details and full announcement for any limits.
Assistance Listing (CFDA)
93.853
Official source
View on Grants.gov ↗
Application URL
www.grants.gov/search-results-detail/361452 ↗Apply through Grants.gov (Workspace) using the application package on the official listing, unless the full announcement names a different submission system.
Source identifier
Grants.gov opportunity ID 361452 · Funding opportunity number RFA-NS-26-032
Posted
March 11, 2026 · Source last updated March 11, 2026
Last verified
October 29, 2026 (against Grants.gov)
Data completeness
92% of key fields published by the sourceNot published: published funding range.
Record confidence
mediumforecast — dates and amounts are agency estimates.

Eligibility details (from the agency)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

Description (from the official listing)

The National Institute of Neurological Disorders and Stroke (NINDS) is interested in supporting ambitious research projects to elucidate mechanisms of neurodegeneration in Alzheimer’s disease-related dementias (ADRD) organized as a “Center without Walls” consortium. NINDS Centers without Walls are collaborative research networks that bring together diverse expertise from different institutions to tackle complex neurological problems that are not tractable by individual research projects.This program is considering using an activity code, such as the RM1, that enables interdisciplinary research consortia capable of identifying and characterizing novel ADRD mechanisms. Teams may include cross-disciplinary and cross-specialty expertise to address the complex co-pathologies, mixed etiologies, and disease heterogeneity in ADRD.This program is anticipated to support teams that can combine multiple approaches, such as state-of-the-art technologies, disease-relevant models, clinical science, and human specimens, to investigate unique disease mechanisms and identify new therapeutic targets, biomarkers, and other factors influencing ADRD susceptibility, resilience, and pathology. One awardee team would serve as a coordinating center for all awardees to facilitate recurring meetings, data harmonization and sharing, cross-site communication, and support the implementation of inter-laboratory rigor and reproducibility plans.This program is informed by key priorities from the ADRD Summit 2025, including embracing ADRD complexity and breaking down topic- and disease-based silos, and is…

Read the full description

The National Institute of Neurological Disorders and Stroke (NINDS) is interested in supporting ambitious research projects to elucidate mechanisms of neurodegeneration in Alzheimer’s disease-related dementias (ADRD) organized as a “Center without Walls” consortium. NINDS Centers without Walls are collaborative research networks that bring together diverse expertise from different institutions to tackle complex neurological problems that are not tractable by individual research projects.This program is considering using an activity code, such as the RM1, that enables interdisciplinary research consortia capable of identifying and characterizing novel ADRD mechanisms. Teams may include cross-disciplinary and cross-specialty expertise to address the complex co-pathologies, mixed etiologies, and disease heterogeneity in ADRD.This program is anticipated to support teams that can combine multiple approaches, such as state-of-the-art technologies, disease-relevant models, clinical science, and human specimens, to investigate unique disease mechanisms and identify new therapeutic targets, biomarkers, and other factors influencing ADRD susceptibility, resilience, and pathology. One awardee team would serve as a coordinating center for all awardees to facilitate recurring meetings, data harmonization and sharing, cross-site communication, and support the implementation of inter-laboratory rigor and reproducibility plans.This program is informed by key priorities from the ADRD Summit 2025, including embracing ADRD complexity and breaking down topic- and disease-based silos, and is intended to provide a mechanistic foundation for future translational and clinical ADRD research.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Investigators with complementary expertise in ADRD mechanisms, clinical phenotypes, and advanced technologies are encouraged to contact agency staff listed below for additional information.

Agency contact

NINDS ADRD Administration and Program Staff
NINDSDONADRD@mail.nih.gov

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